Be sure to talk about those, too. Avoid condoms with spermicide, which can irritate the rectum. Here we go with the lube talk again! Going full speed ahead could do some major damage. You can also get other STIs from anal sex. What to do during the main event. This is also the time to discuss any concerns you have and set clear boundaries. This is because the delicate tissues in the anus are prone to irritation and tears, which can allow bacteria to enter. What to Know for Your First Time.
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