For the transformation, see Yes Mother Transformation. Purist - Defeat Mom for the first time. All of her attacks will deal a full heart of damage. Have a Heart - Defeat Mom for the 1st time. Mom's fight takes place in the entirety of the room and always begins with Mom stomping in the center of the room. This article is about the boss. Once Mom is defeated, all enemies spawned by Mom will die as well, except for Globins. She can stomp on Isaac, which is telegraphed by a growing shadow and her screaming.
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